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β-Casomorphin, bovine TFA
CAS No. ——
β-Casomorphin, bovine TFA ( β-Casomorphin-7 (bovine) (TFA); Bovine β-casomorphin-7 TFA )
产品货号. M29705 CAS No. ——
β-Casomorphin, bovine TFA (β-Casomorphin-7 (bovine) TFA) is a opioid peptide with an IC50 of 14 μM in an Opioid receptors binding assay.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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生物学信息
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产品名称β-Casomorphin, bovine TFA
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述β-Casomorphin, bovine TFA (β-Casomorphin-7 (bovine) TFA) is a opioid peptide with an IC50 of 14 μM in an Opioid receptors binding assay.
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产品描述β-Casomorphin, bovine TFA (β-Casomorphin-7 (bovine) TFA) is a opioid peptide with an IC50 of 14 μM in an Opioid receptors binding assay.(In Vitro):β-Casomorphin, bovine TFA (0.1μM; 30 minutes-24 hours) stimulates the secretion of mucin in DHE Cells after 8 h of treatment. β-Casomorphin, bovine TFA (0.1μM; 24 hours) induces an increase in rMuc2 and rMuc3 mRNA levels. β-Casomorphin, bovine TFA does not modify the expression of rMuc1, rMuc4, and rMuc5AC. β-Casomorphin, bovine TFA (0.1μM; 24 hours) stimulates MUC5AC expression and mucin Secretion in HT29-MTX Cells (human).(In Vivo):β-Casomorphin, bovine TFA (7.5×10?6 mol/day/kg ; i.g.; for 30 days) increases plasma insulin and decreased plasma glucagon of diabetic rats. β-Casomorphin, bovine TFA (7.5×10?6 mol/day/kg ; i.g.; for 30 days) alters the changes of SOD, GPx, T-AOC, MDA and H2O2 in the kidney of diabetic rats. β-Casomorphin, bovine TFA (7.5×10?6 mol/day/kg ; i.g.; for 30 days) reduces MDA (significantly) and H2O2 (non-significantly) level in the kidney compared to the diabetic rats. β-Casomorphin, bovine TFA (7.5×10?6 mol/day/kg ; i.g.; for 30 days) alleviates high glucose-induced decreasement in SOD and GPx activity, increasement in MDA contents in the NRK-52E cells.
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同义词β-Casomorphin-7 (bovine) (TFA); Bovine β-casomorphin-7 TFA
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通路Others
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靶点Other Targets
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受体IC50: 14 μM (Opioid receptor)
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研究领域——
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适应症——
化学信息
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CAS Number——
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分子量903.9
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分子式C43H56F3N7O11
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称Sequence:Tyr-Pro-Phe-Pro-Gly-Pro-Ile
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
Brantl V, et al. Opioid activities of beta-casomorphins. Life Sci. 1981 Apr 27;28(17):1903-9.
产品手册
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